143632-19-3Relevant articles and documents
Recognition of all four base pairs of double-helical DNA by triple-helix formation: Design of nonnatural deoxyribonucleosides for pyrimidine-purine base pair binding
Griffin, Linda C.,Kiessling, Laura L.,Beal, Peter A.,Gillespie, Paul,Dervan, Peter B.
, p. 7976 - 7982 (2007/10/02)
The sequence-specific recognition of double-helical DNA by oligonuclcotide-directed triple-helix formation is limited mostly to purine tracts. Design leads that could expand the recognition code to all four Watson-Crick base pairs would provide one step t