143654-59-5

Basic information

• Product Name: Methyl 3-(2-fluorophenyl)propanoate
• Synonyms: Methyl 3-(2-fluorophenyl)propanoate;Benzenepropanoic acid, 2-fluoro-, Methyl ester;Methyl 2-fluorobenzenepropanoate
• CAS NO: 143654-59-5
• Molecular Formula: C₁₀H₁₁FO₂
• Molecular Weight: 182.1915432
• Mol File: 143654-59-5.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 3-(2-fluorophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-(2-fluorophenyl)propanoate(143654-59-5)
• EPA Substance Registry System: Methyl 3-(2-fluorophenyl)propanoate(143654-59-5)

Safety Data

• Hazardous Substances Data: 143654-59-5(Hazardous Substances Data)

Usage

General Description

Methyl 3-(2-fluorophenyl)propanoate is a chemical compound with the molecular formula C11H13FO2. It is a methyl ester of 3-(2-fluorophenyl)propanoic acid and is commonly used as a flavoring agent or fragrance in various products. This chemical is a clear, colorless liquid with a fruity odor and is commonly found in perfumes, soaps, and other household products. It is known for its potential to cause eye and skin irritation, and it should be handled and used with caution in controlled environments. Overall, Methyl 3-(2-fluorophenyl)propanoate is a versatile compound with various applications in the fragrance and flavor industry.

Upstream product

• 186581-53-3 diazomethane 
• 451-69-4 2-fluorocinnamic acid 
• 67-56-1 methanol 
• 1643-26-1 3-(2-fluorophenyl)propionic acid 
• 59845-58-8 C₁₀H₉FO₂ 
• 18944-77-9 2-fluorocinnamic acid 
• 446-52-6 2-Fluorobenzaldehyde 
• 104201-65-2 methyl (2E)-3-(2-fluorophenyl)prop-2-enoate 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 76727-24-7 3-(2-fluorophenyl)propan-1-ol 
• 1269625-73-1 5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-ol 
• 1269625-74-2 5-(2-fluoro-benzyl)-2-pyridin-3-yl-pyrimidin-4-ol 
• 1269625-75-3 4-chloro-5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidine 
• 1269625-76-4 4-chloro-5-(2-fluoro-benzyl)-2-pyridin-3-yl-pyrimidine 
• 1269625-77-5 [5-(2-Fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-isopropyl-amine 
• 1269625-79-7 Diethyl-[5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-amine 
• 1269625-80-0 Cyclohexylmethyl-[5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-amine 
• 1269625-81-1 4-[5-(2-Fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-morpholine 
• 1269625-82-2 5-(2-Fluoro-benzyl)-4-piperidin-1-yl-2-pyridin-2-yl-pyrimidine 
• 1269625-84-4 [5-(2-Fluoro-benzyl)-2-pyridin-3-yl-pyrimidin-4-yl]-isopropyl-amine 
• 1269625-85-5 5-(2-Fluoro-benzyl)-4-(4-methyl-piperazin-1-yl)-2-pyridin-2-yl-pyrimidine 
• 221631-40-9 dimethyl-4-(2-fluorophenyl)-2-oxo-butylphosphonate 

Relevant articles and documents

Reduction of Electron-Deficient Alkenes Enabled by a Photoinduced Hydrogen Atom Transfer

Direct hydrogen atom transfer from a photoredox-generated Hantzsch ester radical cation to electron-deficient alkenes has enabled the development of an efficient formal hydrogenation under mild, operationally simple conditions. The HAT-driven mechanism is supported by experimental and computational studies. The reaction is applied to a variety of cinnamate derivatives and related structures, irrespective of the presence of electron-donating or electron-withdrawing substituents in the aromatic ring and with good functional group compatibility. (Figure presented.).

Photodriven Transfer Hydrogenation of Olefins

An improved practical method for the photodriven diimide reduction of olefins was investigated. This catalyst-free procedure proceeds at ambient temperature, utilizes air as oxidant and a lower hydrazine loading, and produces inert nitrogen gas as the sole byproduct. Several functional groups were tolerated, and in some cases, the reaction was chemoselective. Challenging substrates such as cinnamate ester derivatives and trans-stilbene were reduced in excellent yields. The small amount of UVA rays emitted from a household compact fluorescent light bulb was proposed to enable the cis/trans isomerization of the diimide and to promote the loss of hydrogen from the diimide.

AROMATIC C16-C20-SUBSTITUTED TETRAHYDRO PROSTAGLANDINS USEFUL AS FP AGONISTS

The invention provides novel PGF analogs. In particular, the present invention relates to compounds having a structure according to the following formula: wherein R1, R2, R3, R4, X, Y, and Z are defined below. This invention also includes optical isomers, diastereomers and enantiomers of the formula above, and pharmaceutically-acceptable salts, biohydrolyzable amides, esters, and imides thereof. The compounds of the present invention are useful for the treatment of a variety of diseases and conditions, such as bone disorders and glaucoma. Accordingly, the invention further provides pharmaceutical compositions comprising these compounds. The invention still further provides methods of treatment for bone disorders and glaucoma using theses compounds or the compositions containing them.