14371-25-6

Basic information

• Product Name: Benzene, (1-bromo-2,2-dimethoxyethyl)-
• CAS NO: 14371-25-6
• Molecular Formula: C10H13BrO2
• Molecular Weight: 245.116
• Mol File: 14371-25-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzene, (1-bromo-2,2-dimethoxyethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (1-bromo-2,2-dimethoxyethyl)-(14371-25-6)
• EPA Substance Registry System: Benzene, (1-bromo-2,2-dimethoxyethyl)-(14371-25-6)

Safety Data

• Hazardous Substances Data: 14371-25-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 38608-46-7 acetic acid-(α,β-dibromo-phenethyl ester) 
• 4747-15-3 1-(2-methoxyvinyl)benzene 
• 124-41-4 sodium methylate 
• 122-78-1 phenylacetaldehyde 
• 56-23-5 tetrachloromethane 
• 10521-96-7 styryl acetate 
• 7726-95-6 bromine 
• 101-48-4 phenylacetaldehyde dimethyl acetal 
• 117531-39-2 1-phenyl-1-methoxy-2-bromo-2-phenylselenenyl ethane, erythro 
• 60466-40-2 (E)-phenyl(styryl)selane 
• 14371-19-8 cis-β-methoxystyrene 

Downstream Products

• 85725-95-7 1-<2-(β,β-dimetossi-α-feniletiltio)fenil>pirrolo 
• 4362-17-8 phenylketene ethylene acetal 
• 6836-98-2 3-phenyldihydrofuran-2-one 
• 4360-62-7 2-(α-bromobenzyl)-1,3-dioxolane 
• 91166-86-8 1-<5-trifluoro-2-(β,β-dimetossi-α-feniletiltio)fenil>pirrolo 
• 91166-87-9 1-<5-metossi-2-(β,β-dimetossi-α-feniletiltio)fenil>pirrolo 
• 91166-85-7 1-<5-cloro-2-(β,β-dimetossi-α-feniletilo)fenil>pirrolo 
• 122774-93-0 4-Bromo-3-methoxy-4-phenyl-butyric acid methyl ester 
• 93718-40-2 6-chloro-3-(chloro-phenyl-methyl)-1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide 
• 33603-16-6 (β-bromo-styryl)-methyl ether 
• 16927-13-2 α-bromophenylacetaldehyde 
• 329794-04-9 [2-(5-Phenyl-thiazol-2-ylamino)-pyridin-6-yl]-methanol 
• 38509-24-9 [2,2-dimethoxy-1-(phenylsulfonyl)ethyl]benzene 
• 38509-26-1 α-Phenylsulfonyl-β-methoxy-styrol 

Relevant articles and documents

Structure and thermal reactivity of some 2-substituted 1,3-oxathiolane S-oxides

Isomerization of 2-benzylidene-1,3-dioxolane to 3-phenylbutyrolactone occurs readily under flash vacuum pyrolysis (FVP) conditions. 2-Diphenylmethyl-1,3-oxathiolane and 2-benzyl-1,3-oxathiolane have been prepared and the latter compound has been oxidized to the corresponding sulfoxide, whose structure and conformation are examined by 1H NMR, and to the sulfone whose X-ray structure is determined. 2-Benzylidene-1,3-oxathiolane is also prepared and the behavior of the three S-oxidized oxathiolane derivatives upon FVP is examined. While extrusion of SOn to give ethene and a carbonyl compound predominates in all three cases, the sulfoxide gives also bis(2-hydroxyethyl) disulfide, most likely formed via thiirane S-oxide and 1,2-oxathietane.

ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF

The present invention is directed to compounds of formula (I) (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

BROMINATION OF DIMETHYLACETALS WITH Br2-CHLOROTRIMETHYLSILANE-NaBr

α-Bromodimethylacetals are obtained in excellent yields by treating dimethylacetals with Br2-NaBr-chlorotrimethylsilane in CH3OH/CH3CN (2:1). The method is suitable for large scale preparation.