14372-50-0

Basic information

• Product Name: 1-butoxy-4-thiocyanatobenzene
• Synonyms: 1-butoxy-4-thiocyanatobenzene
• CAS NO: 14372-50-0
• Molecular Weight: 207.296
• Mol File: 14372-50-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-butoxy-4-thiocyanatobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-butoxy-4-thiocyanatobenzene(14372-50-0)
• EPA Substance Registry System: 1-butoxy-4-thiocyanatobenzene(14372-50-0)

Safety Data

• Hazardous Substances Data: 14372-50-0(Hazardous Substances Data)

Upstream product

• 1126-79-0 n-butyl phenyl ether 
• 540-72-7 sodium thiocyanide 
• 4344-55-2 para-butoxyaniline 
• 333-20-0 potassium thioacyanate 
• 7677-24-9 trimethylsilyl cyanide 

Relevant articles and documents

Fluorium-Initiated Dealkylative Cyanation of Thioethers to Thiocyanates

Thioethers are converted to thiocyanates via fluorium-initiated dealkylative cyanation. Selectfluor is used as the oxidant, and trimethylsilyl cyanide is used as the cyanation reagent. The well-streamlined procedure is user-friendly, operationally simple, and step-economical. The current mechanistic studies show that the sulfur radical cation and cyano radical are both involved. They combine to deliver cyanosulfonium, an intermediate toward thiocyanate after dealkylation. Alternatively, a nucleophilic mechanism is also possible. Our dealkyaltive cyanation is also efficient in synthesizing thiocyanates with strongly electrophilic functionalities.