143810-77-9

Basic information

• Product Name: Thiophene, 2-[(4-methylphenyl)sulfinyl]-, (S)-
• CAS NO: 143810-77-9
• Molecular Formula: C11H10OS2
• Molecular Weight: 222.332
• Mol File: 143810-77-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thiophene, 2-[(4-methylphenyl)sulfinyl]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-[(4-methylphenyl)sulfinyl]-, (S)-(143810-77-9)
• EPA Substance Registry System: Thiophene, 2-[(4-methylphenyl)sulfinyl]-, (S)-(143810-77-9)

Safety Data

• Hazardous Substances Data: 143810-77-9(Hazardous Substances Data)

Upstream product

• 2786-07-4 2-thienyl lithium 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 
• 188290-36-0 thiophene 
• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 5713-61-1 thiophen-2-yl magnesium bromide 
• 190448-84-1 (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide 

Relevant articles and documents

Asymmetric synthesis of chiral sulfoxides and sulfinimines by using N-sulfinylsultam

Bornane-10,2-sultam 1 is stereoselectively converted by DMAP-assisted sulfinylation to diastereomerically pure (2R)-N-[(R)-p-tolylsulfinyl]-bornane-10,2-sultam 2 in 77% yield. The crystalline sulfinylating agent 2 reacts with a variety of nucleophiles to afford sulfoxides 3 and sulfinimines 5 in excellent yields and enantioselectivities.

Syntheses of Enantiomerically Pure Furyl and Thienyl p-Tolyl Sulfoxides

We report a highly enantioselective reaction of Grignard reagents, derived from simple furans or thiophene, with (-)-(S)-menthylsulfinate to give in high yield enantiomerically pure furyl and thienylsulfoxides.