1438558-71-4

Basic information

• Product Name: (4-(tert-butyl)phenyl)(quinolin-8-yl)methanone
• Synonyms: (4-(tert-butyl)phenyl)(quinolin-8-yl)methanone
• CAS NO: 1438558-71-4
• Molecular Weight: 289.377
• Mol File: 1438558-71-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4-(tert-butyl)phenyl)(quinolin-8-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(tert-butyl)phenyl)(quinolin-8-yl)methanone(1438558-71-4)
• EPA Substance Registry System: (4-(tert-butyl)phenyl)(quinolin-8-yl)methanone(1438558-71-4)

Safety Data

• Hazardous Substances Data: 1438558-71-4(Hazardous Substances Data)

Upstream product

• 38707-70-9 8-formylquinoline 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 40245-26-9 quinoline-8-carboxylic acid methyl ester 
• 86-59-9 8-carboxyquinoline 
• 106-49-0 p-toluidine 
• 25428-06-2 2-amino-5-methyl-acetophenone 
• 54885-04-0 phenyl(quinolin-8-yl)methanone 
• 551-93-9 2-aminoacetophenone 
• 56234-20-9 1-(quinolin-8-yl)ethan-1-one 

Relevant articles and documents

Rhodium(III)-Catalyzed Direct Coupling of Quinoline-8-Carbaldehydes with (Het)Arylboronic Acids for the Synthesis of 8-Aryloylquinolines

Herein, we describe a method for the synthesis of aryl-(het)aryl ketones by Rh(III)-catalyzed direct coupling between quinoline-8-carbaldehydes and (het)arylboronic acids. The method has a broad substrate scope, a high functional group tolerance, and uses

Direct exchange of a ketone methyl or aryl group to another aryl group through ciC bond activation assisted by rhodium chelation

Swapped: Commercially available quinolinone derivatives (1 or 2, see scheme) were reacted with arylboronic acids in the presence of a RhI complex to give aryl(quinolin-8-yl)methanone products 3 in medium to good yields. A mechanism that involves the in situ oxidation of RhI to RhIII by O2 in the presence of CuI was proposed. Copyright