1439393-44-8

Basic information

• Product Name: (1-{4-[2-(3-hydroxy-pyrrolidin-1-yl)-8-pyridin-2-yl-purin-9-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester
• Synonyms: (1-{4-[2-(3-hydroxy-pyrrolidin-1-yl)-8-pyridin-2-yl-purin-9-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester
• CAS NO: 1439393-44-8
• Molecular Weight: 527.626
• Mol File: 1439393-44-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-{4-[2-(3-hydroxy-pyrrolidin-1-yl)-8-pyridin-2-yl-purin-9-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1-{4-[2-(3-hydroxy-pyrrolidin-1-yl)-8-pyridin-2-yl-purin-9-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester(1439393-44-8)
• EPA Substance Registry System: (1-{4-[2-(3-hydroxy-pyrrolidin-1-yl)-8-pyridin-2-yl-purin-9-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester(1439393-44-8)

Safety Data

• Hazardous Substances Data: 1439393-44-8(Hazardous Substances Data)

Upstream product

• 1439391-60-2 {1-[4-(5-amino-2-chloro-pyrimidin-4-ylamino)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester 
• 1439391-58-8 {1-[4-(2-chloro-5-nitro-pyrimidin-4-ylamino)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester 
• 1259224-00-4 [1-(4-amino-phenyl)-cyclobutyl]-carbamic acid tert-butyl ester 
• 40499-83-0 pyrrolidin-3-ol 
• 1439393-21-1 tert-butyl 1-(4-(2-chloro-8-(pyridin-2-yl)-9H-purin-9-yl)phenyl)cyclobutylcarbamate 

Downstream Products

• 1439393-41-5 1-(9-(4-(1-aminocyclobutyl)phenyl)-8-(pyridin-2-yl)-9H-purin-2-yl)pyrrolidin-3-ol 

Relevant articles and documents

BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula 1: wherein Het, X, R1 and R2 are as defined herein.