1439401-68-9

Basic information

• Product Name: 3,3-bis(4-methoxyphenyl)-N-methyl-N-phenylacrylamide
• Synonyms: 3,3-bis(4-methoxyphenyl)-N-methyl-N-phenylacrylamide
• CAS NO: 1439401-68-9
• Molecular Weight: 373.452
• Mol File: 1439401-68-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,3-bis(4-methoxyphenyl)-N-methyl-N-phenylacrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-bis(4-methoxyphenyl)-N-methyl-N-phenylacrylamide(1439401-68-9)
• EPA Substance Registry System: 3,3-bis(4-methoxyphenyl)-N-methyl-N-phenylacrylamide(1439401-68-9)

Safety Data

• Hazardous Substances Data: 1439401-68-9(Hazardous Substances Data)

Upstream product

• 17792-18-6 3,3-bis(4-methoxyphenyl)propenoic acid 
• 100-61-8 N-methylaniline 

Relevant articles and documents

Metal-Free Synthesis of 3-Arylquinolin-2-ones from Acrylic Amides via a Highly Regioselective 1,2-Aryl Migration: An Experimental and Computational Study

Combined experimental and theoretical investigations into the phenyliodine bis(trifluoroacetate) (PIFA)-mediated reaction of N-arylcinnamamide to produce 3-arylquinolin-2-one derivatives have been conducted. High regioselectivity during the aryl migration process was observed in 3,3-disubstituted acrylamides. Density functional theory calculation was conducted in an attempt to understand the mechanism and the origin of the regioselectivity. On the basis of both the experimental and the theoretical results, a mechanism involving an oxidative annulation, followed by an aryl migration, has been proposed. The annulation is the regioselectivity determining step.