143995-03-3

Basic information

• Product Name: Adenosine, N-formyl-N-methyl-2',3'-O-(1-methylethylidene)-
• CAS NO: 143995-03-3
• Molecular Formula: C15H19N5O5
• Molecular Weight: 349.346
• Mol File: 143995-03-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Adenosine, N-formyl-N-methyl-2',3'-O-(1-methylethylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, N-formyl-N-methyl-2',3'-O-(1-methylethylidene)-(143995-03-3)
• EPA Substance Registry System: Adenosine, N-formyl-N-methyl-2',3'-O-(1-methylethylidene)-(143995-03-3)

Safety Data

• Hazardous Substances Data: 143995-03-3(Hazardous Substances Data)

Upstream product

• 19083-21-7 2',3'-O-isopropylidene-N₆,N₆'-dimethyladenosine 

Relevant articles and documents

N6-Substituent Effect on the Photooxidation of 2',3'-O-Isopropylideneadenosines with a Pyrimidopteridinetetraone N-Oxide. Chemical Evidence for the Generation and Reactivity of Adenosyl Cation Radicals

A comparative study on the photooxidation of 2',3'-O-isopropylideneadenosine 1a and its N6-benzoyl, N-6-monomethyl, and N6,N6-dimethyl derivatives, 1b-d, with a pyrimidopteridinetetraone N-oxide (PPO) was carried out.The ease of photooxidative consumption of the adenosines by the PPO is in the order 1d > 1c > 1a > 1b, which is parallel to their oxidation-peak potentials.Although substrates 1a and 1b underwent oxidative intramolecular cyclisation to the corresponding 5'-O,8-cycloadenosines, 2a and 2b, even in low yield, substrates 1c and 1d were exclusively oxidised at the N6-methyl group to give the corresponding N6-formyl derivatives, 3 and 4, together with minor amounts of demethylated products, 1a and 1c.The present observations provide chemical evidence for the generation and reactivity of adenosyl cation radicals.