144089-96-3

Basic information

• Product Name: DMT-2'-F-dGiBu
• Synonyms: DMT-2'-F-dGiBu;N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide;5'-DMT-2'-F-ibu-dG;5-O-DMT-N2-ISOBUTYRYL-2-FLUORO-2-DEOXYGUANOSINE
• CAS NO: 144089-96-3
• Molecular Formula: C₃₅H₃₆FN₅O₇
• Molecular Weight: 657.6880432
• Mol File: 144089-96-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.16±0.20(Predicted)
• CAS DataBase Reference: DMT-2'-F-dGiBu(CAS DataBase Reference)
• NIST Chemistry Reference: DMT-2'-F-dGiBu(144089-96-3)
• EPA Substance Registry System: DMT-2'-F-dGiBu(144089-96-3)

Safety Data

• Hazardous Substances Data: 144089-96-3(Hazardous Substances Data)

Usage

General Description

DMT-2'-F-dGiBu is a chemical compound that is a modification of the psychedelic substance DMT (N,N-Dimethyltryptamine). The compound features a fluoro substitution at the 2' position of the indole ring and a butyl group attached to the dimethylamine moiety. This modification is thought to enhance the potency and duration of the psychoactive effects of DMT. The compound is classified as a tryptamine derivative and is known for its hallucinogenic effects, producing profound alterations in perception, mood, and cognition. DMT-2'-F-dGiBu is a novel compound that has attracted interest in the field of psychedelic research and has the potential to further our understanding of the effects of DMT on the brain and consciousness.

Upstream product

• 78842-13-4 2'-deoxy-2'-fluoroguanosine 
• 129835-17-2 9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine 
• 200404-37-1 Trifluoro-methanesulfonic acid (2R,3S,4R,5R)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-5-(tetrahydro-pyran-2-yloxymethyl)-tetrahydro-furan-3-yl ester 
• 146954-65-6 N²-isobutyryl-9-(2-O-isobutyryl-3,5-O-(tetraisopropyldisiloxanylene)-β-D-arabinofuranosyl)guanine 
• 146954-67-8 Isobutyric acid (2R,3S,4R,5R)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-5-(tetrahydro-pyran-2-yloxymethyl)-tetrahydro-furan-3-yl ester 
• 146954-69-0 N²-isobutyryl-9-(2-fluoro-3,5-di-O-tetrahydropyran-2-yl-β-D-arabinofuranosyl)guanine 
• 146954-68-9 N²-isobutyryl-9-(3,5-di-O-tetrahydropyran-2-yl-β-D-arabinofuranosyl)guanine 
• 146954-66-7 N²-isobutyryl-9-(2-O-isobutyryl-β-D-arabinofuranosyl)guanine 
• 129835-15-0 2-amino-9-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-1H-purin-6(9H)-one 
• 69304-44-5 3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 80681-25-0 2’-fluoro-N2-isobutyryl-2’-deoxyguanosine 

Downstream Products

• 1337865-42-5 C₄₄H₄₃FN₈O₉ 

Relevant articles and documents

2′-Fluoro-c-di-GMP as an oral vaccine adjuvant

Bis-(3′-5′)-cyclic dimeric 2′-deoxy-2′-fluoroguanosine monophosphate (2′-F-c-di-GMP) was synthesized through the modified H-phosphonate chemistry. Oral immunization of C57BL/6 mice with Helicobacter pylori cell-free sonicate extract adjuvanted with 2′-F-c

COMPOSITIONS AND METHODS FOR ACTIVATING "STIMULATOR OF INTERFERON GENE" -DEPENDENT SIGNALLING

The present invention provides highly active cyclic-di-nucleotide (CDN) immune stimulators that activate DCs via a recently discovered cytoplasmic receptor known as STING (Stimulator of Interferon Genes), In particular, the CDNs of the present invention a