144128-67-6

Basic information

• Product Name: 1,3-Cyclohexanedione, 5-[3-(trifluoroMethyl)phenyl]-
• Synonyms: 1,3-Cyclohexanedione, 5-[3-(trifluoroMethyl)phenyl]-;5-[3-(Trifluoromethyl)phenyl]cyclohexane-1,3-dione;3-Hydroxy-5-[3-(trifluoromethyl)-phenyl]cyclohex-2-en-1-one
• CAS NO: 144128-67-6
• Molecular Formula: C₁₃H₁₁F₃O₂
• Molecular Weight: 256.2204496
• EINECS: -0
• Mol File: 144128-67-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1,3-Cyclohexanedione, 5-[3-(trifluoroMethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclohexanedione, 5-[3-(trifluoroMethyl)phenyl]-(144128-67-6)
• EPA Substance Registry System: 1,3-Cyclohexanedione, 5-[3-(trifluoroMethyl)phenyl]-(144128-67-6)

Safety Data

• Hazardous Substances Data: 144128-67-6(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 13 carbon atoms, 11 hydrogen atoms, 3 fluorine atoms, and 2 oxygen atoms.

Explanation

The compound is derived from cyclohexanedione, which is a six-membered ring with two carbonyl groups (C=O) at the 1 and 3 positions.

Explanation

The compound has a phenyl group (a six-membered ring with alternating single and double bonds) with a trifluoromethyl group (-CF3) attached to the 3rd position of the phenyl ring.

Explanation

The compound is used as a building block in the production of various compounds due to its unique structure and functional groups.

Explanation

The compound is studied for its potential as a building block in the development of new drugs, particularly due to the presence of the trifluoromethyl group.

Explanation

The compound has been investigated for its interactions with other molecules and its potential biological activities, which could lead to the development of new drugs or therapies.

Explanation

The compound's unique structure and functional groups allow it to interact with other molecules, which can be useful in the development of new drugs and agrochemicals.

Explanation

The presence of the trifluoromethyl group in the compound makes it a valuable building block for the development of new drugs and agrochemicals due to its unique properties and potential for various applications.

Derivative of cyclohexanedione

Yes

Contains a trifluoromethylphenyl group

Yes

Application in organic synthesis

Yes

Application in pharmaceutical research

Yes

Potential biological activities

Yes

Interactions with other molecules

Yes

Valuable building block for new drugs and agrochemicals

Yes

Upstream product

• 84175-48-4 1-[3-(trifluoromethyl)phenyl]but-1-en-3-one 
• 454-89-7 3-Trifluoromethylbenzaldehyde 

Downstream Products

• 80061-33-2 7-chloro-3,4-dihydro-10-hydroxy-3-<3-(trifluoromethyl)phenyl>-1,9(2H, 10H)-acridinedione 

Relevant articles and documents

Synthesis and Antimalarial Properties of 1-Imino Derivatives of 7-Chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and Related Structures

To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.