144149-81-5 Usage
Structure
A derivative of isoquinolinecarboxylic acid with a 4-chlorobenzoyl group attached to the 2-position of the tetrahydro-1,2,3,4-tetrahydroisoquinoline core.
Appearance
White solid.
Molecular weight
335.77 g/mol.
Usage
Building block in organic synthesis, used in the pharmaceutical industry for the synthesis of various pharmaceutical drugs and in the development of new chemical entities.
Pharmacological activities
Potential pharmacological activities are being researched for therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 144149-81-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,1,4 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 144149-81:
(8*1)+(7*4)+(6*4)+(5*1)+(4*4)+(3*9)+(2*8)+(1*1)=125
125 % 10 = 5
So 144149-81-5 is a valid CAS Registry Number.
144149-81-5Relevant articles and documents
The dakin-west reaction of N-acyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acids using trifluoroacetic anhydride: Structural revision for the unexpected product
Kawase, Masami,Okada, Youichi,Miyamae, Hiroshi
, p. 285 - 294 (2007/10/03)
The Dakin-West reaction of N-pivaloyl- and N-benzoyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acids (1a-e) with trifluoroacetic anhydride yielded unexpectedly 1-(1-acyloxy-2,2,2-trifluoroethyl)-3,4-dihydroisoquinoline derivatives (3a-e) in good yields.
