144219-96-5Relevant articles and documents
Nuclear fluorination of 3,5-diarylisoxazoles with Selectfluor
Stephens, Chad E.,Blake, Jacqueline A.
, p. 1939 - 1945 (2004)
C-4 Fluorination of a series of 3,5-diarylisoxazoles has been accomplished using the N-F reagent Selectfluor. With substrates containing neutral or activating substituents on the 5-phenyl ring, acetonitrile at room temperature or at reflux coul
PhIO/Et3N ? 3HF-Mediated Formation of Fluorinated 2H-Azirines via Domino Fluorination/Azirination Reaction of Enamines
Zhang, Yong,Zhao, Xiaoyuan,Zhuang, Chen,Wang, Senlin,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 2107 - 2112 (2018/04/19)
A variety of enamine carboxylic esters and enaminones were converted to the biologically interesting fluorinated 2H-azirines through reactions with PhIF2 generated in situ by PhIO and Et3N ? 3HF in 1,2-dichroloethane, which features the hypervalent iodine reagents-mediated introduction of fluorine atom and formation of the 2H-azirine skeleton under metal-free conditions. The domino reaction is postulated to proceed via a PhIF2-mediated oxidative fluorination and a subsequent azirination of the fluorinated enamine intermediates. (Figure presented.).
Fluorination of 4-nitroisoxazoline salts. Synthesis of 4-fluoro-4- nitroisoxazolines and 4-fluoroisoxazoles
Khisamutdinov,Okhlobystina,Fainzil'Berg
experimental part, p. 2182 - 2184 (2011/01/08)
Methods for the synthesis of hitherto unknown 4-fluoro-4-nitroisoxazolines by fluorination of 4-nitroisoxazoline salts with FClO3 in MeOH and 4-fluoroisoxazoles by treatment of fluoronitroisoxazolines bearing the hydrogen atom bound to the C(5)
