144314-48-7Relevant articles and documents
Preparation of Monosilyl Ethers of Vicinal Diols
Antonsen, Oyvind,Benneche, Tore,Undheim, Kjell
, p. 757 - 760 (2007/10/02)
Monosilyl-protected vicinal diols can be prepared by lithiation of silyl derivatives of α-hydroxyalkylstannanes and subsequent addition to carbonyl compounds.Concurrent reaction of the lithium species initially formed is a reverse Brook rearrangement to yield α-hydroxyalkylsilanes.Alternatively, the monosilyl protected diols were prepared by a samarium(II) iodide mediated Barbier type reaction between α-haloalkoxysilanes and carbonyl compounds.