1443222-00-1

Basic information

• Product Name: 1-butyl-4-hydroxy-5-oxo-2-p-tolyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester
• Synonyms: 1-butyl-4-hydroxy-5-oxo-2-p-tolyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester
• CAS NO: 1443222-00-1
• Molecular Weight: 317.385
• Mol File: 1443222-00-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-butyl-4-hydroxy-5-oxo-2-p-tolyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-butyl-4-hydroxy-5-oxo-2-p-tolyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester(1443222-00-1)
• EPA Substance Registry System: 1-butyl-4-hydroxy-5-oxo-2-p-tolyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester(1443222-00-1)

Safety Data

• Hazardous Substances Data: 1443222-00-1(Hazardous Substances Data)

Upstream product

• 7554-12-3 diethylmalate 
• 104-87-0 4-methyl-benzaldehyde 
• 109-73-9 N-butylamine 
• 108-56-5 diethyl oxaloacetate 
• 104-84-7 para-methylbenzylamine 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 

Relevant articles and documents

DIKETOPYRROLOPYRROLES HAVING THREE DIFFERENT SUBSTITUENTS AS EMITTERS OF YELLOW, ORANGE AND RED LIGHT, AND THE METHOD OF THEIR PREPARATION

New derivatives of diketopyrrolopyrroles (well-known organic pigments) having three different substituents and a new method of obtaining them have been disclosed. These dyes can be used as highly fluorescent substances with advantageous properties. These compounds can be obtained by the method according to the invention in no more than a four-step synthesis from simple, readily available and cheap substrates.

Cu catalyzed cross-dehydrogenative coupling reaction for the synthesis of 3-hydroxy-2-pyrrolidinones

A new convenient strategy for the synthesis of 3-hydroxy-2-pyrrolidinone derivatives featuring regioselective C–C coupling has been developed. This is a Cu (II) catalyzed cross dehydrogenative coupling (CDC) involving enamino-ketones of benzyl amines and di-alkyl acetylenedicarboxylate, followed by cyclization by primary amines. TBHP (tert-butyl hydroperoxide) has been used as the oxidant to promote the coupling protocol. This synthetic route principally demonstrates the scope of CDC reaction and also applicable to gram-scale synthesis.