1443309-03-2

Basic information

• Product Name: C₂₆H₂₂F₂NO₂⁽¹⁺⁾*Br^(1-)
• Synonyms: C₂₆H₂₂F₂NO₂⁽¹⁺⁾*Br^(1-)
• CAS NO: 1443309-03-2
• Molecular Weight: 498.367
• Mol File: 1443309-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₂F₂NO₂⁽¹⁺⁾*Br^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₂F₂NO₂⁽¹⁺⁾*Br^(1-)(1443309-03-2)
• EPA Substance Registry System: C₂₆H₂₂F₂NO₂⁽¹⁺⁾*Br^(1-)(1443309-03-2)

Safety Data

• Hazardous Substances Data: 1443309-03-2(Hazardous Substances Data)

Upstream product

• 28188-37-6 2-(bromomethyl)benzoic acid isopropyl ester 
• 777097-57-1 1-(3,5-difluorophenyl)isoquinoline 

Relevant articles and documents

Enantioselective iridium-catalyzed hydrogenation of 1- and 3-substituted isoquinolinium salts

Asymmetric hydrogenation: The title reaction provides an efficient and rapid access to chiral 1- and 3-substituted 1,2,3,4-tetrahydroisoquinolines with excellent enantioselectivity (see scheme; L=ligand). A preliminary mechanistic study indicates that the 1,2-hydride addition might be the initial step in the reaction. The method has been used in the synthesis of urinary antispasmodic drug (+)-solifenacin. Copyright