1443323-58-7Relevant articles and documents
Indium mediated allylation of WteRR-butanesulftnyl imines with 1,3-dibromopropene: Stereoselective synthesis of aziridines
Maciá, Edgar,Foubelo, Francisco,Yus, Miguel
, p. 248 - 266 (2019/07/31)
- The reaction of TV-fer?-butanesulfinyl imines 1 with 1,3-dibromopropene (2), in the presence of indium metal, in saturated aqueous solution of sodium bromide, produced bromohomoallylamine derivatives 3 with total facial diastereoselectivity for the imine addition, and moderate yields. These compounds were easily transformed into the corresponding vinyl aziridines 5 upon deprotonation with KHMDS in THF, the intramolecular cyclization taking place in a stereospecific manner in moderate to high yields.