1443465-27-7

Basic information

• Product Name: 1-ethoxy-3,4-diphenyl-1H-2,1-benzoxaphosphorin-1-oxide
• Synonyms: 1-ethoxy-3,4-diphenyl-1H-2,1-benzoxaphosphorin-1-oxide
• CAS NO: 1443465-27-7
• Molecular Weight: 362.365
• Mol File: 1443465-27-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-ethoxy-3,4-diphenyl-1H-2,1-benzoxaphosphorin-1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethoxy-3,4-diphenyl-1H-2,1-benzoxaphosphorin-1-oxide(1443465-27-7)
• EPA Substance Registry System: 1-ethoxy-3,4-diphenyl-1H-2,1-benzoxaphosphorin-1-oxide(1443465-27-7)

Safety Data

• Hazardous Substances Data: 1443465-27-7(Hazardous Substances Data)

Upstream product

• 4546-19-4 ethyl hydrogen phenylphosphonate 
• 501-65-5 diphenyl acetylene 
• 65-85-0 benzoic acid 
• 928-49-4 hex-3-yne 
• 1443991-49-8 1,2,3,4,5-pentadeuteriophenyl phosphonic monoethyl ester 
• 1754-49-0 diethyl phenylphosphonate 
• 1942-46-7 5-decyne 

Relevant articles and documents

Photoredox/Cobalt-Catalyzed Phosphinyloxy Radical Addition/Cyclization Cascade: Synthesis of Phosphaisocoumarins

A novel visible-light photoredox-catalyzed phosphinyloxy radical addition/cyclization cascade of arylphosphinic acids or arylphosphonic acid monoesters with alkynes has been developed, which provides an efficient and practical access to various phosphaisocoumarins by using a dual catalytic system containing an acridinium photosensitizer and a cobaloxime proton-reducing catalyst [Co(dmgH)2]PyCl at ambient temperature. This method has advantages of a broad substrate scope, mild condition, as well as no sacrificial oxidant.

Rhodium-catalyzed oxidative C-H activation/cyclization for the synthesis of phosphaisocoumarins and phosphorous 2-pyrones

Rhodium-catalyzed cyclization of phosphinic acids and phosphonic monoesters with alkynes has been developed. The oxidative annulation proceeds with complete conversion of phosphinic acid derivatives and allowed the atom-economic preparation of useful phosphaisocoumarins with high yield and selectivity. The reaction is tolerant of extensive substitution on the phosphinic acid, phosphonic monoester and alkyne, including halides, ketone, and hydroxyl groups as substituents. Furthermore, we found that alkenylphosphonic monoesters proceed to give a wide range of phosphorus 2-pyrones through oxidative annulation with alkynes. Mechanistic studies revealed that Ci￡H bond metalation was the rate-limiting step. Copyright

Synthesis of phosphaisocoumarins through rhodium-catalyzed cyclization using alkynes and arylphosphonic acid monoesters

A rhodium-catalyzed cyclization using alkynes and arylphosphonic acid monoesters for the synthesis of phosphaisocoumarins is reported. A number of arylphosphonic acid monoesters were selectively cyclized in high yields with functional group tolerance. In addition, unsymmetrical alkynes are applied in high regioselectivity.