1443674-08-5Relevant articles and documents
Direct synthesis of β-N-glycosides by the reductive glycosylation of azides with protected and native carbohydrate donors
Zheng, Jianbin,Urkalan, Kaveri Balan,Herzon, Seth B.
, p. 6068 - 6071 (2013/06/27)
A simple and straightforward method for the stereocontrolled synthesis of β-linked N-glycosides uses alkyl and aryl azides as the nitrogen source. The N-glycosides are formed in high yields and with high βselectivities (typically >70 % yield, >15:1 β:α selectivity). This approach is also amenable to the synthesis of N-glycosylated amino acids and peptides (see example, Fmoc=9-fluorenylmethoxycarbonyl). Copyright