1443774-76-2

Basic information

• Product Name: (R)-methyl 3-(benzyloxy)-6-cyano-5-oxohexanoate
• Synonyms: (R)-methyl 3-(benzyloxy)-6-cyano-5-oxohexanoate
• CAS NO: 1443774-76-2
• Molecular Weight: 275.304
• Mol File: 1443774-76-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-methyl 3-(benzyloxy)-6-cyano-5-oxohexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-methyl 3-(benzyloxy)-6-cyano-5-oxohexanoate(1443774-76-2)
• EPA Substance Registry System: (R)-methyl 3-(benzyloxy)-6-cyano-5-oxohexanoate(1443774-76-2)

Safety Data

• Hazardous Substances Data: 1443774-76-2(Hazardous Substances Data)

Upstream product

• 32328-03-3 diethyl 3-hydroxyglutarate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 838906-52-8 diethyl 3-(benzyloxy)pentanedioate 
• 838906-36-8 meso-4-(benzyloxy)glutaric anhydride 
• 112904-69-5 (R)-3-(benzyloxy)-5-methoxy-5-oxopentanoic acid 
• 1443774-74-0 (5R)-dimethyl 5-(benzyloxy)-2-cyano-3-oxoheptanedioate 

Downstream Products

• 791115-50-9 methyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 
• 1574495-27-4 methyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 

Relevant articles and documents

Asymmetric synthesis of the HMG-CoA reductase inhibitor atorvastatin calcium: An organocatalytic anhydride desymmetrization and cyanide-free side chain elongation approach

An efficient asymmetric synthesis of atorvastatin calcium has been achieved from commercially available diethyl 3-hydroxyglutarate through a novel approach that involves an organocatalytic enantioselective cyclic anhydride desymmetrization to establish C(