1443991-22-7

Basic information

• Product Name: ethyl 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylate
• Synonyms: ethyl 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylate
• CAS NO: 1443991-22-7
• Molecular Weight: 437.882
• Mol File: 1443991-22-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylate(1443991-22-7)
• EPA Substance Registry System: ethyl 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylate(1443991-22-7)

Safety Data

• Hazardous Substances Data: 1443991-22-7(Hazardous Substances Data)

Upstream product

• 703-23-1 2'-hydroxy-6'-methoxyacetophenone 
• 2040-04-2 2,6-dimethoxyacetophenone 
• 23834-14-2 7-chloro-4-hydrazinoquinoline 
• 1443991-21-6 ethyl 4-(2,6-dimethoxyphenyl)-4-hydroxy-2-oxobut-3-enoate 

Downstream Products

• 1146757-92-7 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid 
• 1443991-23-8 tert-butyl 2-[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxamido]adamantane-2-carboxylate 
• 146362-70-1 merclinertant 
• 1443991-26-1 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carbonyl chloride 

Relevant articles and documents

The synthesis of neurotensin antagonist SR 48692 for prostate cancer research

An improved synthesis of the molecule SR 48692 is presented and its use as a neurotensin antagonist biological probe for use in cancer research is described. The preparation includes an number of enhanced chemical conversions and strategies to overcome some of the limiting synthetic transformations in the original chemical route.