144403-09-8

Basic information

• Product Name: Carbamic acid, [4-oxo-4-[(phenylmethyl)amino]butyl]-, 1,1-dimethylethyl ester
• CAS NO: 144403-09-8
• Molecular Formula: C16H24N2O3
• Molecular Weight: 292.378
• Mol File: 144403-09-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [4-oxo-4-[(phenylmethyl)amino]butyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [4-oxo-4-[(phenylmethyl)amino]butyl]-, 1,1-dimethylethyl ester(144403-09-8)
• EPA Substance Registry System: Carbamic acid, [4-oxo-4-[(phenylmethyl)amino]butyl]-, 1,1-dimethylethyl ester(144403-09-8)

Safety Data

• Hazardous Substances Data: 144403-09-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 57294-38-9 N-(tert-butoxycarbonyl)-4-aminobutanoic acid 
• 100-46-9 benzylamine 
• 85909-08-6 tert-butyl 2-oxopyrrolidine-1-carboxylate 

Downstream Products

• 103621-64-3 4-amino-N-benzylbutyramide 
• 74758-09-1 4-Amino-N-benzyl-butyramide; hydrochloride 
• 1217508-86-5 4-O-(((benzyl)amino)-4-oxobutyl)carbamoylazithromycin 11,12-cyclic carbonate 

Relevant articles and documents

A new powerful method for the transformation of lactams into ω-amino-carboxamides under high pressure conditions

High-pressure reaction of N-Boc-lactams with amines provides an efficient entry to ω-N-Boc-aminocarboxamide derivatives.

BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS

The present application provides methods and catalysts for activation of carboxylic acids for organic reactions. In particular, methods are disclosed for direct nucleophilic addition reactions, such as, amidation reactions with amines, cycloadditions, and conjugate additions, using boronic acid catalysts of formula I, II or III: Also included are novel boronic acid catalysts of formula IV, V and III:

Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4-O-carbamate derivatives

A series of novel 11,12-cyclic carbonate azithromycin 4″-O-carbamate derivatives were designed, synthesized and evaluated for their in vitro antibacterial activities. Compounds 7b and 7d were the most effective (0.5 and 0.5 μg ml 1) against two strains of