144461-82-5

Basic information

• Product Name: 2-(α-hydroxy-3-fluorobenzyl)-2-phenyl-1,3-dithiane
• CAS NO: 144461-82-5
• Molecular Weight: 320.452
• Mol File: 144461-82-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(α-hydroxy-3-fluorobenzyl)-2-phenyl-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(α-hydroxy-3-fluorobenzyl)-2-phenyl-1,3-dithiane(144461-82-5)
• EPA Substance Registry System: 2-(α-hydroxy-3-fluorobenzyl)-2-phenyl-1,3-dithiane(144461-82-5)

Safety Data

• Hazardous Substances Data: 144461-82-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 5425-44-5 2-Phenyl-[1,3]dithiane 
• 456-48-4 3-Fluorobenzaldehyde 

Downstream Products

• 70028-84-1 5-(3-fluorophenyl)-5-phenylhydantoin 

Relevant articles and documents

A convenient preparation of symmetrical and unsymmetrical 1,2-diketones: Application to fluorinated phenytoin synthesis

1,2-Diketones are efficiently produced in two steps by reaction of aldehydes with anions derived from 2-substituted dithianes followed by treatment of the resulting alcoholis with NBS in aqueous acetone; phenytoin derivatives were prepared from these diketones by a standard method involving treatment with urea and potassium hydroxide under reflux.