144464-68-6

Basic information

• Product Name: Benzoic acid, 4-acetyl-, pentafluorophenyl ester
• CAS NO: 144464-68-6
• Molecular Formula: C15H7F5O3
• Molecular Weight: 330.211
• Mol File: 144464-68-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-acetyl-, pentafluorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-acetyl-, pentafluorophenyl ester(144464-68-6)
• EPA Substance Registry System: Benzoic acid, 4-acetyl-, pentafluorophenyl ester(144464-68-6)

Safety Data

• Hazardous Substances Data: 144464-68-6(Hazardous Substances Data)

Upstream product

• 864069-04-5 pentafluorophenyl 4-vinylbenzoate 
• 99-93-4 4-Hydroxyacetophenone 
• 201230-82-2 carbon monoxide 
• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 109613-00-5 4-acetophenyl triflate 

Downstream Products

• 53689-84-2 4-acetylbenzophenone 

Relevant articles and documents

Iron-Catalyzed Wacker-type Oxidation of Olefins at Room Temperature with 1,3-Diketones or Neocuproine as Ligands**

Herein, we describe a convenient and general method for the oxidation of olefins to ketones using either tris(dibenzoylmethanato)iron(III) [Fe(dbm)3] or a combination of iron(II) chloride and neocuproine (2,9-dimethyl-1,10-phenanthroline) as catalysts and phenylsilane (PhSiH3) as additive. All reactions proceed efficiently at room temperature using air as sole oxidant. This transformation has been applied to a variety of substrates, is operationally simple, proceeds under mild reaction conditions, and shows a high functional-group tolerance. The ketones are formed smoothly in up to 97 % yield and with 100 % regioselectivity, while the corresponding alcohols were observed as by-products. Labeling experiments showed that an incorporated hydrogen atom originates from the phenylsilane. The oxygen atom of the ketone as well as of the alcohol derives from the ambient atmosphere.