144486-27-1

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-[(4-methylphenyl)amino]-3-phenyl-
• CAS NO: 144486-27-1
• Molecular Formula: C17H15N3O2
• Molecular Weight: 293.325
• Mol File: 144486-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(4-methylphenyl)amino]-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(4-methylphenyl)amino]-3-phenyl-(144486-27-1)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-[(4-methylphenyl)amino]-3-phenyl-(144486-27-1)

Safety Data

• Hazardous Substances Data: 144486-27-1(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 5759-75-1 6-chloro-3-phenylpyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 79157-12-3 3,7-Diphenyl-10-(4-methylphenyl)pyrido<2,3-d:6,5-d'>dipyrimidine-2,4,6,8(1H,3H,7H,10H)-tetraone 

Relevant articles and documents

Autorecycling Oxidation of Alcohols Catalysed by Pyridopyrimidines as an NAD(P)(1+) Model

Two kinds of pyridopyrimidines as new NAD-type redox catalysts, 3,7,10-trisubstituted pyridodipyrimidine-2,4,6,8(1H,3H,7H,10H)-tetraones 6 and 3,8,10-trisubstituted pyridodipyrimidine-2,4,6(3H,7H,10H)-triones 7, have been synthesized by the condensation of 6-(substituted-amino)uracils 9 and 6-(substituted-amino)-2-phenylpyrimidin-4(3H)-ones 11 with appropriate 6-chloro-5-formyluracils 12 or 2,4,6-trichloropyrimidine-5-carbaldehyde 13 in dimethylformamide (DMF) or acetic acid.Compounds 6 and 7 have been found to oxidize a variety of alcohols under neutral conditions (in the absence of base) to yield the corresponding carbonyl compounds, catalytically with a markedly high turnover number.The oxidation yields were promoted remarkably depending upon the presence of lipophilic substituents, particularly due to the presence of longer alkyl groups at the 10-position.These catalysts are so stable that the oxidation reaction proceeds until the substrate is exhausted.