144492-44-4

Basic information

• Product Name: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-[[(phenylmethyl)imino]methyl]-, 1,1-dimethylethyl ester, (R)-
• CAS NO: 144492-44-4
• Molecular Formula: C18H26N2O3
• Molecular Weight: 318.416
• Mol File: 144492-44-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-[[(phenylmethyl)imino]methyl]-, 1,1-dimethylethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-[[(phenylmethyl)imino]methyl]-, 1,1-dimethylethyl ester, (R)-(144492-44-4)
• EPA Substance Registry System: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-[[(phenylmethyl)imino]methyl]-, 1,1-dimethylethyl ester, (R)-(144492-44-4)

Safety Data

• Hazardous Substances Data: 144492-44-4(Hazardous Substances Data)

Upstream product

• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 100-46-9 benzylamine 

Downstream Products

• 144492-64-8 (3S,4S)-3-amino-1-benzyl-4-<(R)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidin-4-yl>azetidin-2-one 
• 316821-35-9 (R)-3-[(2S,3R)-2-((R)-1-Amino-2-hydroxy-ethyl)-1-benzyl-4-oxo-azetidin-3-yl]-4-phenyl-oxazolidin-2-one 
• 110289-27-5 cis-(3R,4R)-1-benzyl-4-formyl-3-<(4R)-2-oxo-4-phenyloxazolidin-3-yl>azetidin-2-one 
• 135821-30-6 (4R,3'R,4'R)-3-<4'-(hydroxymethyl)-2'-oxo-1'-(phenylmethyl)-3'-azetidinyl>-4-phenyl-2-oxazolidinone 
• 234755-06-7 acetic acid 3(S)-{benzyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2(R)-{[(tert-butoxy)carbonyl]amino}-5-(trimethylsilyl)pent-4-yn-1-yl ester 
• 234755-10-3 tert-butyl (1S,4R)-[1-benzyl-(9H-fluoren-9-ylmethoxycarbonylamino)]-2,2-dimethyloxazolidine-3-carboxylate 
• 234755-11-4 tert-butyl (1S,4R)-2-[N-(9H-fluoren-9-ylmethoxycarbonyl)-benzylamino]-(1-hydroxymethyl-4-trimethylsilylbut-3-ynyl)carbamate 
• 234755-04-5 tert-butyl (3aR,4R)-3-benzyl-4-isopropenyloxymethyl-2-oxo-1-p-toluenesulfonyl-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-d]imidazole-5-carboxylate 
• 234755-09-0 tert-butyl (3aR,4R)-3-benzyl-4-acetoxymethyl-2-oxo-1-p-toluenesulfonyl-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-d]imidazole-5-carboxylate 

Relevant articles and documents

Alkylidenecarbene insertion into a nitrogen lone pair: An unexpected synthesis of dihydropyrroles from alkynyliodonium salts

A novel intramolecular reaction between an alkylidenecarbene and the lone pair of electrons on a carbamate's nitrogen is described. The reaction occurs preferentially over an available 1,5 C-H insertion and gives substituted dihydropyrroles upon workup.

N,Se-acetals: Easy preparation and application to radical mediated EPC synthesis

A facile synthesis of N,S- and N,Se-acetals starting from aldehydes and primary amines is presented. These acetals are used as precursors for radical reactions. The stereoselectivity of the reactions depends on the radical trap used.

Contribution to the development of new substitution patterns of optically active β-lactams: Synthesis of homochiral 4-(1-aminoalkyl)azetidin-2-ones from N-(tert-butyloxycarbonyl) α-amino aldehyde-derived imines via asymmetric Staudinger reaction

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