1445138-66-8

Basic information

• Product Name: 1-methyl-2-phenyl-3-(p-tolylethynyl)-1H-indole
• Synonyms: 1-methyl-2-phenyl-3-(p-tolylethynyl)-1H-indole
• CAS NO: 1445138-66-8
• Molecular Weight: 321.422
• Mol File: 1445138-66-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-phenyl-3-(p-tolylethynyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-phenyl-3-(p-tolylethynyl)-1H-indole(1445138-66-8)
• EPA Substance Registry System: 1-methyl-2-phenyl-3-(p-tolylethynyl)-1H-indole(1445138-66-8)

Safety Data

• Hazardous Substances Data: 1445138-66-8(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 54655-08-2 N,N-dimethyl-2-(2-phenylethynyl)aniline 
• 766-97-2 4-n-methylphenylacetylene 

Relevant articles and documents

Palladium-catalyzed coupling of ortho-alkynylanilines with terminal alkynes under aerobic conditions: Efficient synthesis of 2,3-disubstituted 3-alkynylindoles

Two nucleophiles, one triple bond: Under aerobic conditions, palladium-catalyzed direct coupling of o-alkynylanilines and terminal alkynes took place smoothly to afford the 2,3-disubstituted 3-alkynylindoles 3 in good to excellent yields. The intermediate A was characterized and a retro-aminopalladation of B was observed for the first time. Copyright