144514-38-5 Usage
Description
3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline is a versatile chemical compound that features an acetyl-piperazinyl group and a chloroaniline group. 3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline is recognized for its potential applications across various industries due to its unique structural and functional attributes. The acetyl-piperazinyl group serves as a valuable building block in drug design, while the chloroaniline group is a well-known precursor in the synthesis of dyes and pigments. Its diverse utility is further enhanced by its intermediate role in the synthesis of pharmaceuticals and organic compounds, making it a compound of interest in chemical, pharmaceutical, and material sciences.
Uses
Used in Pharmaceutical Industry:
3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs. The acetyl-piperazinyl group embedded within its structure is particularly advantageous for creating molecules with specific therapeutic properties.
Used in Chemical Industry:
In the chemical industry, 3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline is utilized as a precursor in the production of dyes and pigments, capitalizing on the reactivity and functional group chemistry of the chloroaniline component.
Used in Material Industry:
3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline also finds application in the material industry, where its structural features can be employed to engineer materials with tailored properties for specific uses, such as in the development of new polymers or composites.
It is crucial to handle 3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline with appropriate safety measures, given its potential health and environmental risks if mismanaged. Proper management and disposal protocols are essential to mitigate any adverse effects associated with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 144514-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,5,1 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 144514-38:
(8*1)+(7*4)+(6*4)+(5*5)+(4*1)+(3*4)+(2*3)+(1*8)=115
115 % 10 = 5
So 144514-38-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H16ClN3O/c1-9(17)15-4-6-16(7-5-15)12-8-10(14)2-3-11(12)13/h2-3,8H,4-7,14H2,1H3
144514-38-5Relevant articles and documents
STUDIES ON PYRIDONECARBOXYLIC ACIDS. 1. SYNTHESIS AND ANTIBACTERIAL EVALUATION OF 7-SUBSTITUTED-6-HALO-4-OXO-4H-THIAZETOQUINOLINE-3-CARBOXYLIC ACIDS
Segawa, Jun,Kitano, Masahiko,Kazuno, Kenji,Matsuoka, Masato,Shirahase, Ichiro,et al.
, p. 4727 - 4738 (2007/10/02)
A series of thiazetoquinoline-3-carboxylic acids and their esters were prepared and evaluated for antibacterial activity.The derivatives with a hydrogen or methyl group at C-1, fluorine at C-6, and piperazinyl or 4-methyl-1-piperazinyl group at C-7 showed superior in vitro antibacterial activity, and the derivatives with 4-methyl-1-piperazinyl group at C-7 had potent in vivo activity.Compound 29a (NM394) showed excellent in vitro antibacterial activity and low toxicity but poor absorption from the gastrointestinal tract.Compound 29ee (NM441), an N- derivative of 29a, was found to possess a favorable pharmacokinetic profile and oral activity superior to that of ciprofloxacin in experimental animals.
