1446021-66-4Relevant articles and documents
JAK KINASE INHIBITOR, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF IN FIELD OF MEDICINE
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, (2022/01/24)
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Substituted heteroaryl compound and composition and application thereof
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, (2016/10/10)
The invention provides a substituted heteroaryl compound, a composition thereof and application of the substituted heteroaryl compound and the composition. The compound is a compound shown in a formula (I) or a stereisomer, or a tautomer, or nitric oxide, or solvate, or a metabolite, or a pharmaceutically acceptable salt or a prodrug of the compound shown in the formula (I). The invention further provides the drug composition containing the compound, and the compound and the drug composition can adjust activity of JAK kinase and are used for preventing, handling, treating, and relieving diseases or disorder mediated by the JAK kinase.
SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE
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, (2015/07/07)
The present invention provides new heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof useful in preventing, treating or lessening the severity of JAK-mediated diseases. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of JAK-mediated diseases.