144620-11-1 Usage
General Description
3-(4-Fluoro-phenyl)-pyrrolidine is a chemical compound with the molecular formula C10H12FN. It is a pyrrolidine derivative, consisting of a pyrrolidine ring with a 4-fluorophenyl group attached to the third carbon atom. 3-(4-FLUORO-PHENYL)-PYRROLIDINE is commonly used in the field of medicinal chemistry and pharmaceutical research for the development of potential drug candidates. It exhibits a range of pharmacological activities and has been investigated for its potential as a therapeutic agent in various medical conditions. Additionally, it is used as a building block in the synthesis of other organic compounds and can be utilized in the development of new materials and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 144620-11-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,6,2 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 144620-11:
(8*1)+(7*4)+(6*4)+(5*6)+(4*2)+(3*0)+(2*1)+(1*1)=101
101 % 10 = 1
So 144620-11-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H12FN/c11-10-3-1-8(2-4-10)9-5-6-12-7-9/h1-4,9,12H,5-7H2
144620-11-1Relevant articles and documents
N-Substituted-3-arylpyrrolidines: Potent and Selective Ligands at Serotonin 1A Receptor
Ahn, Kyo Han,Lee, Seok Jong,Lee, Chang-Ho,Hong, Chang Y.,Park, Tae Kyo
, p. 1379 - 1384 (2007/10/03)
3-Arylpyrrolidines are synthesized through the coupling of N-benzyl-3-(methanesulfonyloxy)pyrrolidine with diarylcuprates. Pharmacological evaluation of a series of N-substituted-3-arylpyrrolidines toward several neurotransmitter receptors indicated that some of them are good ligands for serotonin 1A receptor. Particularly, N-pyrrolidines were found to be potent and selective ligands. A preliminary biological evaluation for several selected compounds indicated that they are potentially effective antianxiety and antidepressant agents.
