1446757-51-2

Basic information

• Product Name: 3,4-bis(hydroxymethyl)benzonitrile
• Synonyms: 3,4-bis(hydroxymethyl)benzonitrile
• CAS NO: 1446757-51-2
• Molecular Weight: 163.176
• Mol File: 1446757-51-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,4-bis(hydroxymethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-bis(hydroxymethyl)benzonitrile(1446757-51-2)
• EPA Substance Registry System: 3,4-bis(hydroxymethyl)benzonitrile(1446757-51-2)

Safety Data

• Hazardous Substances Data: 1446757-51-2(Hazardous Substances Data)

Upstream product

• 82104-74-3 1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile 

Downstream Products

• 89877-62-3 6-cyanoisobenzofuran-1(3H)-one 
• 82104-74-3 1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile 

Relevant articles and documents

Synthesis of 1,2-phenylenedimethanols by base-promoted reduction of isobenzofuran-1(3H)-ones with silane

An efficient method for preparation of substituted 1,2-phenylenedimethanols and aliphatic 1,4-diols that are valuable intermediates in organic synthesis, has been developed by the base-promoted reduction of isobenzofuran-1(3H)-ones and γ-lactones with silane under mild conditions. Compared with traditional procedures using stoichiometric amounts of metal hydrides and alkyl reductants, the present method avoids the use of sensitive reagents and is operationally simple and a broad variety of functional groups are tolerated.