144710-45-2

Basic information

• Product Name: Carbamic acid, (tetrahydro-3-thienyl)-, 1,1-dimethylethyl ester, (S)- (9CI)
• Synonyms: Carbamic acid, (tetrahydro-3-thienyl)-, 1,1-dimethylethyl ester, (S)- (9CI)
• CAS NO: 144710-45-2
• Molecular Formula: C9H17NO2S
• Molecular Weight: 203.30178
• Product Categories: N-BOC
• Mol File: 144710-45-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (tetrahydro-3-thienyl)-, 1,1-dimethylethyl ester, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (tetrahydro-3-thienyl)-, 1,1-dimethylethyl ester, (S)- (9CI)(144710-45-2)
• EPA Substance Registry System: Carbamic acid, (tetrahydro-3-thienyl)-, 1,1-dimethylethyl ester, (S)- (9CI)(144710-45-2)

Safety Data

• Hazardous Substances Data: 144710-45-2(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 144786-62-9 (S)-(-)-3-Aminothiolane 

Relevant articles and documents

CARBAMATE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS

The invention provides novel benzoimidazolone-carboxamide-derived carbamate 5-HT4 receptor agonist compounds of formula (I): wherein R1, R2, R3, R4, a, and b are defined in the disclosure. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.

(S)-3-aminothiolane: A new chiral building block

Methioninol [2-amino-4-(methylthio)butan-1-ol] is converted into (S)-4,5-dihydro-4-[2-(methylthio)ethyl]-2-phenyl-1,3-oxazole (1). An acid-catalyzed rearrangement of 1 gives (S)-(-)-3-(benzoylamino)tetrahydrothiophene (2) in a stereospecific fashion. The