144723-59-1

Basic information

• Product Name: 4-Pentenoic acid, 3-ethyl-5-(4-morpholinyl)-5-phenyl-, 1,1-dimethylethyl ester, (E)-
• CAS NO: 144723-59-1
• Molecular Formula: C21H31NO3
• Molecular Weight: 345.482
• Mol File: 144723-59-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Pentenoic acid, 3-ethyl-5-(4-morpholinyl)-5-phenyl-, 1,1-dimethylethyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid, 3-ethyl-5-(4-morpholinyl)-5-phenyl-, 1,1-dimethylethyl ester, (E)-(144723-59-1)
• EPA Substance Registry System: 4-Pentenoic acid, 3-ethyl-5-(4-morpholinyl)-5-phenyl-, 1,1-dimethylethyl ester, (E)-(144723-59-1)

Safety Data

• Hazardous Substances Data: 144723-59-1(Hazardous Substances Data)

Upstream product

• 7196-01-2 4-(1-phenylvinyl)morpholine 
• 81643-03-0 (2E)-2-pentenoic acid tert-butyl ester 
• 136843-98-6 4-((E)-2-Bromo-1-phenyl-vinyl)-morpholine 

Relevant articles and documents

β-Lithiated enamines as enolate equivalents in Michael additions to enoates. A novel entry to mono- and disubstituted 5-oxo esters

Mono-, di- and trisubstituted tert-butyl 5-amino-4-alkenoates 3 and mono- or disubstituted tert-butyl 5-oxoalkanoates 4 are prepared in good overall yield by conjugate addition of β-lithiated enamines to enoates, followed by quenching with water or iodomethane. In all cases, only one stereoisomer of the polysubstituted enamino esters 3 is produced (de > 98%).