1447614-14-3

Basic information

• Product Name: (R)-3-((benzyloxy)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (R)-(+)-N-benzyl-α-methylbenzylamine salt
• Synonyms: (R)-3-((benzyloxy)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (R)-(+)-N-benzyl-α-methylbenzylamine salt
• CAS NO: 1447614-14-3
• Molecular Weight: 550.621
• Mol File: 1447614-14-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-((benzyloxy)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (R)-(+)-N-benzyl-α-methylbenzylamine salt(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((benzyloxy)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (R)-(+)-N-benzyl-α-methylbenzylamine salt(1447614-14-3)
• EPA Substance Registry System: (R)-3-((benzyloxy)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (R)-(+)-N-benzyl-α-methylbenzylamine salt(1447614-14-3)

Safety Data

• Hazardous Substances Data: 1447614-14-3(Hazardous Substances Data)

Upstream product

• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 

Downstream Products

• 767352-29-4 (R)-3-((benzyloxy)amino)-4-(2,4,5-trifluorophenyl)butanoic acid 

Relevant articles and documents

Preparation of Optically Pure ?-Amino Acid Type Active Pharmaceutical Ingredients and Intermediates thereof

The present invention relates to the preparation of optically resolved chiral compounds of β-amino acid type active pharmaceutical ingredients (API), more specifically to β-aminobutyryl substituted compounds and especially β-aminobutyryl compounds having γ-bound aryl groups. The present invention more particularly relates to the preparation of enantiomerically enriched chiral compounds useful as intermediates for the preparation of anti-diabetic agents, preferably sitagliptin.