1447820-23-6

Basic information

• Product Name: C₁₈H₂₇NO₄
• Synonyms: C₁₈H₂₇NO₄
• CAS NO: 1447820-23-6
• Molecular Weight: 321.417
• Mol File: 1447820-23-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₇NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₇NO₄(1447820-23-6)
• EPA Substance Registry System: C₁₈H₂₇NO₄(1447820-23-6)

Safety Data

• Hazardous Substances Data: 1447820-23-6(Hazardous Substances Data)

Upstream product

• 1447820-21-4 C₃₀H₃₅NO₂ 
• 1447820-19-0 tert-butyl 2-((2R,4R,6R)-6-(2-(diallylamino)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate 
• 1447820-18-9 (R)-5-(diallylamino)pentane-1,3-diol 
• 1447820-16-7 (S)-N,N-diallyl-3-hydroxy-5-(trityloxy)pentanethioamide 

Downstream Products

• 442851-51-6 tert-butyl 2-((2R,4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate 
• 134523-00-5 atorvastatin 
• 134395-00-9 (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid t-butyl ester 

Relevant articles and documents

Streamlined catalytic asymmetric synthesis of atorvastatin

An efficient enantioselective synthetic route to atorvastatin was developed based on a direct catalytic asymmetric aldol reaction. The expensive chiral ligand used in the initial aldol reaction was readily recovered (91 %) and reused. Implementation of an oxy-Michael reaction for the construction of the syn-1,3-diol unit eliminated several redundant steps, allowing for rapid access to the common intermediate in six steps (see scheme). Copyright