1447931-36-3Relevant articles and documents
A convenient method to produce [14C]carbon monoxide and its application to the radiosynthesis of [carboxyl-14C]celivarone, [carboxyl-14C]SSR149744
Whitehead, David M.,Hartmann, Sascha,Ilyas, Tenzeela,Taylor, Keith R.,Kohler, Andrew D.,Ellames, George J.
, p. 36 - 41 (2013/05/22)
[carboxyl-14C]Celivarone was synthesised from barium [ 14C]carbonate with overall radiochemical yields in the range 49-53%. The synthetic route involves [14C]carbonylation methodology, which both decreased the number of synthetic steps and increased the yields obtained from previous synthetic routes. [carboxyl-14C]Celivarone was synthesised from barium [14C]carbonate with overall radiochemical yields in the range 49-53%. The synthetic route involves [14C] carbonylation methodology, which both decreased the number of synthetic steps and increased the yields obtained from previous synthetic routes. Copyright