1448245-68-8

Basic information

• Product Name: 2-chloro-N⁶,N⁶-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine
• Synonyms: 2-chloro-N⁶,N⁶-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine
• CAS NO: 1448245-68-8
• Molecular Weight: 702.123
• Mol File: 1448245-68-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-N⁶,N⁶-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N⁶,N⁶-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine(1448245-68-8)
• EPA Substance Registry System: 2-chloro-N⁶,N⁶-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine(1448245-68-8)

Safety Data

• Hazardous Substances Data: 1448245-68-8(Hazardous Substances Data)

Upstream product

• 958-09-8 2'-deoxy-D-adenosine 
• 98-88-4 benzoyl chloride 
• 1448245-67-7 2-nitro-N⁶,N⁶-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine 

Downstream Products

• 4291-63-8 2-chloro-2'-deoxyadenosine 

Relevant articles and documents

A practical synthesis of 2-chloro-2′-deoxyadenosine (Cladribine) from 2′-deoxyadenosine

A practical synthesis of 2-chloro-2′-deoxyadenosine (Cladribine) from 2′-deoxyadenosine is reported. Treatment of fully protected 2′-deoxyadenosine with 2,2,2-trifluoroacetic anhydride and tetrabutylammonium nitrate gave protected 2-nitro-2′-deoxyadenosine with high yield. 2-Chloro-2′-deoxyadenosine was synthesised in four steps and 44.8% yield after substitution by chloride and deprotection steps.