1448887-54-4

Basic information

• Product Name: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-(4-phenylpiperazino)-3-(3-pyridoyl)-5,6-dihydro-4H-thiopyran
• Synonyms: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-(4-phenylpiperazino)-3-(3-pyridoyl)-5,6-dihydro-4H-thiopyran
• CAS NO: 1448887-54-4
• Molecular Weight: 517.716
• Mol File: 1448887-54-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-(4-phenylpiperazino)-3-(3-pyridoyl)-5,6-dihydro-4H-thiopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-(4-phenylpiperazino)-3-(3-pyridoyl)-5,6-dihydro-4H-thiopyran(1448887-54-4)
• EPA Substance Registry System: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-(4-phenylpiperazino)-3-(3-pyridoyl)-5,6-dihydro-4H-thiopyran(1448887-54-4)

Safety Data

• Hazardous Substances Data: 1448887-54-4(Hazardous Substances Data)

Upstream product

• 92-54-6 4-phenyl-1-piperazine 
• 1963-36-6 4-methoxycinnamaldehyde 
• 1312414-21-3 methyl-3-oxo-3-(pyridin-3-yl)propanedithioate 

Relevant articles and documents

Diversity oriented catalyst-free and solvent-free one-pot MCR at room temperature: Rapid and regioselective convergent approach to highly functionalized dihydro-4H-thiopyrans

Highly convergent and regioselective approach to hitherto unreported and synthetically demanding 6-cycloamino-2-(methyl/benzyl)sulfanyl-3-(aroyl/ hetaroyl/alkanoyl)-4-aryl-5,6-dihydro-4H-thiopyrans has been developed via one-pot three-component domino coupling of β-oxodithioesters, α,β-unsaturated aldehydes, and cyclic aliphatic secondary amines at room temperature under catalyst-free and solvent-free conditions. The attractive features of this strategy include mild conditions, short reaction time, high atom-economy, excellent yields, and efficacy of forming three new bonds (C-C, C-N and C-S) and one ring in a single stroke.