1448962-43-3

Basic information

• Product Name: 2-(2-(benzyloxy)phenyl)benzofuran-5-ol
• Synonyms: 2-(2-(benzyloxy)phenyl)benzofuran-5-ol
• CAS NO: 1448962-43-3
• Molecular Weight: 316.356
• Mol File: 1448962-43-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-(benzyloxy)phenyl)benzofuran-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(benzyloxy)phenyl)benzofuran-5-ol(1448962-43-3)
• EPA Substance Registry System: 2-(2-(benzyloxy)phenyl)benzofuran-5-ol(1448962-43-3)

Safety Data

• Hazardous Substances Data: 1448962-43-3(Hazardous Substances Data)

Upstream product

• 31165-67-0 2'-benzyloxyacetophenone 
• 106-51-4 p-benzoquinone 
• 100-39-0 benzyl bromide 
• 118-93-4 o-hydroxyacetophenone 
• 1448962-30-8 C₂₃H₁₈O₄ 
• 1448962-16-0 5-acetoxy-2-hydroxybenzyltriphenylphosphonium bromide 
• 1448962-15-9 5-acetoxy-2-hydroxybenzyl acetate 
• 3524-69-4 2-formyl-1,4-phenylene diacetate 
• 1194-98-5 2,5-Dihydroxybenzaldehyde 

Downstream Products

• 1448962-61-5 C₃₂H₃₆N₂O₃ 

Relevant articles and documents

Synthesis of Benzofurans from Ketones and 1,4-Benzoquinones

Benzofuran derivatives can be synthesized through the sequential Michael addition and cyclization of 1,3-dicarbonyl compounds with 1,4-benzoquinones. However, ketones are rarely used in this reaction because of their low nucleophilicities. In this study, this problem was solved by utilizing triethyl orthoformate, which enabled the formation of a vinyl ethyl ether as an additive. As a result, the nucleophilicity of ketones increased. Many important 5-hydroxybenzofuran derivatives, which were not readily available by synthesis in the past, were also prepared via these newly established reactions. (Figure presented.) .