1449220-60-3

Basic information

• Product Name: D-(+)-menthyl 3-(3-N,N'-diisopropylamino-1(R)-phenyl-propyl)-4-hydroxy-benzoate hydrochloride
• Synonyms: D-(+)-menthyl 3-(3-N,N'-diisopropylamino-1(R)-phenyl-propyl)-4-hydroxy-benzoate hydrochloride
• CAS NO: 1449220-60-3
• Molecular Weight: 530.191
• Mol File: 1449220-60-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: D-(+)-menthyl 3-(3-N,N'-diisopropylamino-1(R)-phenyl-propyl)-4-hydroxy-benzoate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: D-(+)-menthyl 3-(3-N,N'-diisopropylamino-1(R)-phenyl-propyl)-4-hydroxy-benzoate hydrochloride(1449220-60-3)
• EPA Substance Registry System: D-(+)-menthyl 3-(3-N,N'-diisopropylamino-1(R)-phenyl-propyl)-4-hydroxy-benzoate hydrochloride(1449220-60-3)

Safety Data

• Hazardous Substances Data: 1449220-60-3(Hazardous Substances Data)

Upstream product

• 1076199-77-3 racemic 3-(3-N,N'-diisopropylamino-1-phenyl-propyl)-4-hydroxy-benzoic acid 
• 15356-60-2 (1S,2R,5S)-(+)-menthol 
• 1449220-62-5 racemic 3-(3-N,N'-diisopropylamino-1-phenyl-propyl)-4-hydroxy-benzoyl chloride hydrochloride 

Downstream Products

• 194482-44-5 Tolterodine acid 
• 1391913-28-2 (R)-3-(N,N'-diisopropylamino-1-phenyl-propyl)-4-isobutyryloxy-benzoic acid 
• 286930-02-7 fesoterodine 
• 207679-81-0 (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol 
• 286930-03-8 fesoterodine fumarate 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF OPTICALLY PURE FESOTERODINE DERIVATIVES

3,3-diphenylpropylamines of general formula (I), particularly Fesoterodine, as well as their enantiomers, solvates and salts, can be produced by treating a compound of formula (II) with a chiral alcohol to yield the diastereomeric esters of formula (IV) and (IV′), which can be further transformed into a compound of formula (I), or an enantiomer, solvate or salt thereof, wherein R1 is C1-C8 alkyl; and R2 and R3, independently of one another, represent H or C1-C6 alkyl, or together form a ring of 3 to 7 members with the nitrogen to which they are bound.