1449299-44-8

Basic information

• Product Name: C₂₃H₂₄N₂O₃
• Synonyms: C₂₃H₂₄N₂O₃
• CAS NO: 1449299-44-8
• Molecular Weight: 376.455
• Mol File: 1449299-44-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₄N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₄N₂O₃(1449299-44-8)
• EPA Substance Registry System: C₂₃H₂₄N₂O₃(1449299-44-8)

Safety Data

• Hazardous Substances Data: 1449299-44-8(Hazardous Substances Data)

Upstream product

• 18496-54-3 phenylbutyric acid chloride 
• 1449300-08-6 4-phenyl-N-(quinolin-8-yl)butanamide 
• 623-48-3 ethyl iodoacetae 
• 578-66-5 8-amino quinoline 

Relevant articles and documents

Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H Bonds with Primary Alkyl Halides

We report a new set of reactions based on the Pd-catalyzed alkylation of methylene C(sp3)-H bonds of aliphatic quinolyl carboxamides with α-haloacetate and methyl iodide and applications in the stereoselective synthesis of various β-alkylated α-amino acids. These reactions represent the first generally applicable method for the catalytic alkylation of unconstrained and unactivated methylene C-H bonds with high synthetic relevance. When applied with simple isotope-enriched reagents, they also provide a convenient and powerful means to site-selectively incorporate isotopes into the carbon scaffolds of amino acid compounds.