1449412-32-1

Basic information

• Product Name: ethyl 1-phenyl-3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-5-carboxylate
• Synonyms: ethyl 1-phenyl-3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-5-carboxylate
• CAS NO: 1449412-32-1
• Molecular Weight: 421.458
• Mol File: 1449412-32-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 1-phenyl-3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-phenyl-3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-5-carboxylate(1449412-32-1)
• EPA Substance Registry System: ethyl 1-phenyl-3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-5-carboxylate(1449412-32-1)

Safety Data

• Hazardous Substances Data: 1449412-32-1(Hazardous Substances Data)

Upstream product

• 6283-81-4 3-oxo-3-pyridin-3-yl-propionic acid ethyl ester 
• 1449412-24-1 4-(dimethylaminomethylene)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazol-5(4H)-one 
• 21683-61-4 3-(pyridin-3-yl)-1-phenyl-4,5-dihydropyrazol-5-one 

Relevant articles and documents

Microwave-assisted synthesis of some new pyrazolopyridines and their antioxidant, antitumor and antimicrobial activities

The chemical behavior of 4-(dimethylaminomethylene)-1-phenyl-3-(pyridin-3- yl)-1 H-pyrazol-5(4H)-one (enaminone) (2) toward some active methylene reagents has been reported to give pyrazolopyridine derivatives. All the reactions were carried out by conventional heating and microwave irradiation technique. The antioxidant activity of the prepared compounds was studied using 1,1-phenyl-2-picrylhydrazyl (DPPH) assay. Compounds (4c) and (4d) showed the highest activity. The antitumor activity against liver and breast cell lines was tested. Compounds (6), (9) and (11) showed the highest activity for liver cell line while compounds (6) and (9) showed the highest activity for breast cell line. Compounds (4a-d) were screened for their antibacterial activity against Gram-positive, Gram-negative bacteria and antifungal activity.