1449577-86-9Relevant articles and documents
Multi-chromatic pH-activatable 19F-MRI nanoprobes with binary ON/OFF pH transitions and chemical-shift barcodes
Huang, Xiaonan,Huang, Gang,Zhang, Shanrong,Sagiyama, Koji,Togao, Osamu,Ma, Xinpeng,Wang, Yiguang,Li, Yang,Soesbe, Todd C.,Sumer, Baran D.,Takahashi, Masaya,Sherry, A. Dean,Gao, Jinming
supporting information, p. 8074 - 8078 (2013/08/23)
Imaging all the people: Using ionizable diblock copolymers a series of nanoprobes encoded with different 19F reporters for specific pH transitions is prepared for use in MRI. The pH response of the nanoprobes is extremely sharp (ΔpHON/OFF≈0.25 pH), and results from the disassembly of polymer micelles (see scheme). A collection of three nanoprobes provides the proof of concept and allows for a qualitative measurement of environmental pH values. Copyright