1450-62-0

Basic information

• Product Name: 3-(4-methoxyphenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole
• Synonyms: 1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-1,5-diphenyl-; 3-(4-Methoxyphenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole
• CAS NO: 1450-62-0
• Molecular Formula: C₂₂H₂₀N₂O
• Molecular Weight: 328.407
• Mol File: 1450-62-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 484.6°C at 760 mmHg
• Flash Point: 246.9°C
• Density: 1.11g/cm³
• Vapor Pressure: 1.52E-09mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 3-(4-methoxyphenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole(1450-62-0)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole(1450-62-0)

Safety Data

• Hazardous Substances Data: 1450-62-0(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 210561-13-0 2-[4-(4-Chloro-phenyl)-thiazol-2-yl]-4-[3-(4-methoxy-phenyl)-3-oxo-1-phenyl-propyl]-5-methyl-2,4-dihydro-pyrazol-3-one 
• 22966-19-4 trans-4'-methoxychalcone 
• 100-42-5 styrene 
• 20433-10-7 5-(4-methoxyphenyl)-2-phenyl-2H-tetrazole 
• 959-23-9 4'-methoxychalcone 
• 956-02-5 4'-chlorochalcone 
• 59-88-1 phenylhydrazine hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 959-33-1 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 88700-24-7 1-<(methylthio)thiocarbonylmethyl>pyridinium iodide 

Downstream Products

• 95796-91-1 C₂₃H₂₀ClN₃O₄S 
• 105257-76-9 {4-[3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-pyrazol-1-yl]-phenyl}-(4-nitro-phenyl)-diazene 
• 105283-34-9 {4-[3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-pyrazol-1-yl]-phenyl}-p-tolyl-diazene 
• 105283-35-0 (4-Chloro-phenyl)-{4-[3-(4-methoxy-phenyl)-5-phenyl-4,5-dihydro-pyrazol-1-yl]-phenyl}-diazene 
• 92708-91-3 1-(4-Acetylphenyl)-3-(4-methoxyphenyl)-5-phenyl-2-pyrazoline 
• 33045-40-8 3-p-anisyl-1,5-diphenylpyrazole 
• 19361-44-5 1-(4-Nitrophenyl)-3-(4-methoxyphenyl)-5-phenyl-2-pyrazoline 
• 1207173-23-6 1-(4'-thiocyanophenyl)-3-(4'-methoxylphenyl)-5-phenyl-pyrazoline 
• 95797-01-6 4-[3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-pyrazol-1-yl]-benzamide 
• 289725-88-8 1,5-diphenyl-4-ethyl-3-(4'-methoxyphenyl)-1H-pyrazole 
• 113918-28-8 4-{4-[3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-pyrazol-1-yl]-phenyl}-2,6-diphenyl-pyridine 

Relevant articles and documents

Spectroscopic studies of aryl substituted 1-phenyl-2-pyrazolines: Steric and electronic substitution effects

A series of aryl substituted 1-phenyl-2-pyrazolines containing electron-donating and electron-withdrawing substituents on different positions of the C3– or C5-aryl groups were synthesized and their steric and electronic effects on ch

Catalytic Synthesis of Chalcones and Pyrazolines Using Nanorod Vanadatesulfuric Acid: An Efficient and Reusable Catalyst

Nanorod vanadatesulfuric acid (VSA NRs), as a recyclable and ecologically benign catalyst, was used for the one-pot synthesis of chalcones and 1,3,5-triaryl-2-pyrazolines (TAPs). Chalcones were prepared via the condensation of substituted acetophenones with aryl-aldehydes under solvent-free conditions. Subsequently, the synthesized chalcones were used for the catalytic synthesis of TAPs via two-component condensation with phenyl hydrazine in refluxing ethanol. VSA is easily prepared by a simple reaction of chlorosulfonic acid and sodium metavanadate of high purity. Compared to conventional procedures, the present protocol offers several advantages such as simplicity of the procedure, appropriate reaction times, high to excellent yields, easily work-up, recoverability, and reusability of the catalyst, and simple purification of the products.

An eco-friendly synthesis of 2-pyrazoline derivatives catalysed by CeCl 3· 7 H 2O

Abstract: 1,3,5-triaryl-2-pyrazoline derivatives were synthesised by a condensation reaction between chalcones and phenyl hydrazine using cerium chloride heptahydrate as a catalyst. All these reactions were carried out in ethyl lactate (70%) as a green solvent. Easy and efficient work up, recyclability of solvent and catalyst are the key merits of this protocol. Graphical Abstract:: SYNOPSIS A facile protocol for the synthesis of 1,3,5-triaryl-2-pyrazolines is described. The solvent ethyl lactate, obtained from renewable sources, is biodegradable. The catalyst CeCl 3· 7 H 2O is a water-tolerant Lewis acid with low toxicity. Easy and clean work up, recyclable solvent and catalyst are merits of the protocol. The reaction works well for all systems giving good yields of the desired products.[Figure not available: see fulltext.].