1450603-59-4

Basic information

• Product Name: (Z)-1-(octadec-9-en-1-yl)-3-(3-methoxybenzyl)urea
• Synonyms: (Z)-1-(octadec-9-en-1-yl)-3-(3-methoxybenzyl)urea
• CAS NO: 1450603-59-4
• Molecular Weight: 430.674
• Mol File: 1450603-59-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-1-(octadec-9-en-1-yl)-3-(3-methoxybenzyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-(octadec-9-en-1-yl)-3-(3-methoxybenzyl)urea(1450603-59-4)
• EPA Substance Registry System: (Z)-1-(octadec-9-en-1-yl)-3-(3-methoxybenzyl)urea(1450603-59-4)

Safety Data

• Hazardous Substances Data: 1450603-59-4(Hazardous Substances Data)

Upstream product

• 112-77-6 (Z)-9-octadecenoyl chloride 
• 112-80-1 cis-Octadecenoic acid 
• 301-02-0 cis-9-octadecenoamide 
• 112-90-3 (Z)-9-octadecen-1-amine 
• 57198-56-8 1-(isocyanatomethyl)-3-methoxybenzene 

Relevant articles and documents

Macamides and their synthetic analogs: Evaluation of in vitro FAAH inhibition

Maca (Lepidium meyenii), a traditional food crop of the Peruvian Andes is now widely touted as a dietary supplement. Among the various chemical constituents isolated from the plant are a unique series of non-polar, long-chain fatty acid N-benzylamides known as macamides. We have synthesized 11 of the 19 reported macamides and have tested each as potential inhibitors of the human enzyme, fatty acid amide hydrolase (FAAH). The five most potent macamides were FAAH inhibitors (IC50 = 10-17 μM). These amides were derivatives of oleic, linoleic and linolenic acids and benzylamine or 3-methoxybenzylamine. Of the three compounds evaluated in a pre-incubation time study, two macamides were not irreversible inhibitors of FAAH. The third, a carbamate structurally related to macamides, was shown to be an irreversible inhibitor of FAAH (IC50 = 0.153 μM).