1450626-81-9Relevant articles and documents
An efficient one-pot four-component synthesis of functionalized imidazo[1,2-a]pyridines
Movahed, Siyavash Kazemi,Dabiri, Minoo,Bazgir, Ayoob
, p. 525 - 532 (2013/04/24)
An efficient one-pot four-component protocol for the synthesis of imidazo[1,2-a]pyridines was developed by condensing ethane-1,2-diamine (2), 1,1-bis(methylthio)-2-nitroethene (1), aldehydes 3, and activated methylene compounds in EtOH under reflux conditions (Tables 1-3). The features of this procedure are operational simplicity, good yields of products, in situ preparation of heterocyclic ketene aminals (HKA), and catalyst-free conditions. Copyright