1450634-39-5

Basic information

• Product Name: tert-butyl (5-fluoro-1-(2-methyl-5-phenylthiazole-4-carbonyl)piperidin-2-yl)methylcarbamate
• Synonyms: tert-butyl (5-fluoro-1-(2-methyl-5-phenylthiazole-4-carbonyl)piperidin-2-yl)methylcarbamate
• CAS NO: 1450634-39-5
• Molecular Weight: 433.547
• Mol File: 1450634-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (5-fluoro-1-(2-methyl-5-phenylthiazole-4-carbonyl)piperidin-2-yl)methylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (5-fluoro-1-(2-methyl-5-phenylthiazole-4-carbonyl)piperidin-2-yl)methylcarbamate(1450634-39-5)
• EPA Substance Registry System: tert-butyl (5-fluoro-1-(2-methyl-5-phenylthiazole-4-carbonyl)piperidin-2-yl)methylcarbamate(1450634-39-5)

Safety Data

• Hazardous Substances Data: 1450634-39-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1450633-65-4 tert-butyl(1-benzyl-5-fluoro-1,2,3,4-tetrahydropyridin-2-yl)methylcarbamate 
• 1450633-64-3 1-benzyl-2-((tert-butoxycarbonylamino)methyl)-5-fluoropyridiniumbromide 
• 1450633-63-2 tert-butyl(5-fluoropyridin-2-yl)methylcarbamate 
• 1450633-66-5 tert-butyl(5-fluoropiperidin-2-yl)methylcarbamate 
• 13743-09-4 2-methyl-5-phenyl-1,3-thiazole-4-carboxylic acid 
• 561297-96-9 ((5-fluoro-pyridin-2-yl)-methyl)-amine 

Downstream Products

• 1383481-98-8 (5-fluoro-2-((5-(trifluoromethyl)pyridin-2-ylamino)methyl)piperidin-1-yl)(2-methyl-5-phenylthiazol-4-yl)methanone 
• 1450633-67-6 rac-(2-(aminomethyl)-5-fluoropiperidin-1-yl)(2-methyl-5-phenylthiazol-4-yl)methanone 

Relevant articles and documents

SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to compounds that can modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention.