1450759-47-3

Basic information

• Product Name: Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-, hydrochloride (1:1), (αS)-
• Synonyms: Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-, hydrochloride (1:1), (αS)-;(1S,1'S)-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonyl]ethyl-N-(1'-phenylethyl)amine hydrochloride;(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)-N-((S)-1-phenylethyl)ethanamine hydrochloride
• CAS NO: 1450759-47-3
• Molecular Formula: C₂₀H₂₇NO₄S*ClH
• Molecular Weight: 413.96
• Mol File: 1450759-47-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-, hydrochloride (1:1), (αS)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-, hydrochloride (1:1), (αS)-(1450759-47-3)
• EPA Substance Registry System: Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-, hydrochloride (1:1), (αS)-(1450759-47-3)

Safety Data

• Hazardous Substances Data: 1450759-47-3(Hazardous Substances Data)

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 1450657-28-9 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-one 
• 60758-86-3 3-ethoxy-4-methoxybenzenecarbonitrile 

Downstream Products

• 608141-42-0 (S)-2-[1 (3-ethoxy-4-methoxyphenyl)]-1-methanesulfonyl-2-ethylamine 

Relevant articles and documents

PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE

Provided herein are new processes for the preparation of aminosulfone intermediates for the synthesis of 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, which is useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-α. Further provided herein are processes for the commercial production of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethylamine.