1450830-60-0

Basic information

• Product Name: 2-methyl-3-[(phenylmethyl)amino]propane-1-sulfonic acid
• CAS NO: 1450830-60-0
• Molecular Weight: 243.327
• Mol File: 1450830-60-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-3-[(phenylmethyl)amino]propane-1-sulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-3-[(phenylmethyl)amino]propane-1-sulfonic acid(1450830-60-0)
• EPA Substance Registry System: 2-methyl-3-[(phenylmethyl)amino]propane-1-sulfonic acid(1450830-60-0)

Safety Data

• Hazardous Substances Data: 1450830-60-0(Hazardous Substances Data)

Upstream product

• 85980-47-8 S-{2-methyl-3-oxo-3-[(phenylmethyl)amino]propyl}ethanethioate 
• 3219-55-4 N-benzylmethacrylamide 
• 100-46-9 benzylamine 

Relevant articles and documents

Convenient synthesis of various substituted homotaurines from alk-2-enamides

Various substituted homotaurines (=3-aminopropane-1-sulfonic acids) 6 were readily synthesized in satisfactory to good yields via the Michael addition of thioacetic acid to alk-2-enamides 3 (→4), followed by LiAlH4 reduction (→5) and performic acid oxidation (Scheme 1). The configuration of 'anti'-disubstituted homotaurine 'anti'-6h was deduced from the 3-(acetylthio)alkanamide (=S-(3-amino-1,2-dimethyl-3-oxopropyl) ethanethioate)'anti'-4h formed in the Michael addition, which was identified via the Karplus equation analysis, and confirmed by X-ray diffraction analysis. The current route is an efficient method to synthesize diverse substituted homotaurines, including 1-, 2-, and N-monosubstituted, as well as 1,2-, 1,N-, 2,N-, and N,N-disubstituted homotaurines (Table). Copyright