145146-06-1

Basic information

• Product Name: 3-methylene-4-(methylthio)-2-pentyl-4-(trimethylsilyl)cyclobutyl methyl ketone
• CAS NO: 145146-06-1
• Molecular Weight: 298.565
• Mol File: 145146-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methylene-4-(methylthio)-2-pentyl-4-(trimethylsilyl)cyclobutyl methyl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methylene-4-(methylthio)-2-pentyl-4-(trimethylsilyl)cyclobutyl methyl ketone(145146-06-1)
• EPA Substance Registry System: 3-methylene-4-(methylthio)-2-pentyl-4-(trimethylsilyl)cyclobutyl methyl ketone(145146-06-1)

Safety Data

• Hazardous Substances Data: 145146-06-1(Hazardous Substances Data)

Upstream product

• 18402-83-0 (E)-non-3-en-2-one 
• 132118-89-9 1-(methylthio)-1-(trimethylsilyl)-1,2-propadiene 

Relevant articles and documents

Asymmetric [2 + 2] cycloaddition reaction catalyzed by a chiral titanium reagent

In the presence of certain Lewis acids, alkenes containing an alkylthio group (for example, ketene dithioacetals, alkenyl sulfides, alkynyl sulfides, and allenyl sulfides) react with electron deficient olefins to give the corresponding cyclobutane, cyclobutene, or methylene cyclobutane derivatives. By employing a chiral titanium catalyst generated in situ from dichlorodiisopropoxytitanium and a tartrate-derived chiral diol, the [2 + 2] cycloaddition reaction proceeds with high enantioselectivity.